Ng, Kim Tien and Takebe, Yutaka and Kamarulzaman, Adeeba and Tee, Kok Keng (2021) Genome sequencing and phylogenetic reconstruction reveal a potential fourth rhinovirus species and its worldwide distribution. Archives of Virology, 166 (1). pp. 225-229. ISSN 0304-8608, DOI https://doi.org/10.1007/s00705-020-04855-5.
Full text not available from this repository.Abstract
Genome sequences of members of a potential fourth rhinovirus (RV) species, provisionally denoted as rhinovirus A clade D, from patients with acute respiratory infection were determined. Bayesian coalescent analysis estimated that clade D emerged around the 1940s and diverged further around 2006-2007 into two distinctive sublineages (RV-A8-like and RV-A45-like) that harbored unique ``clade-defining'' substitutions. Similarity plots and bootscan mapping revealed a recombination breakpoint located in the 5MODIFIER LETTER PRIME-UTR region of members of the RV-A8-like sublineage. Phylogenetic reconstruction revealed the distribution of clade D viruses in the Asia Pacific region and in Europe, underlining its worldwide distribution.
| Item Type: | Article |
|---|---|
| Funders: | UNSPECIFIED |
| Uncontrolled Keywords: | Genome sequences; Potential fourth rhinovirus species; Rhinovirus A; Phylogenetic reconstruction |
| Subjects: | R Medicine > R Medicine (General) |
| Divisions: | Faculty of Medicine > School of Medicine |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 08 Mar 2022 08:38 |
| Last Modified: | 08 Mar 2022 08:38 |
| URI: | http://eprints.um.edu.my/id/eprint/26501 |
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