Comparing the effectiveness of different dentinal desensitizing agents: In vitro study

Farook, Mohideen S. and Mahmoud, Okba and Ibrahim, Maysara Adnan and Berkathullah, Marwah (2021) Comparing the effectiveness of different dentinal desensitizing agents: In vitro study. BioMed Research International, 2021. ISSN 2314-6133, DOI https://doi.org/10.1155/2021/6652250.

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Abstract

Objectives. To evaluate the in vitro effectiveness of desensitizing agents in reducing dentine permeability. Methods. The efficacy of desensitizing agents in reducing dentine permeability by occluding dentine tubules was evaluated using a fluid filtration device that conducts at 100 cmH(2)O (1.4 psi) pressure, and SEM/EDX analyses were evaluated and compared. Forty-two dentine discs (n=42) of 1 +/- 0.2 mm width were obtained from caries-free permanent human molars. Thirty dentine discs (n=30) were randomly divided into 3 groups (n=10): Group 1: 2.7% wt. monopotassium-monohydrogen oxalate (Mp-Mh oxalate), Group 2: RMGI XT VAR, and Group 3: LIQ SiO2. Dentine permeability was measured following treatment application after 10 minutes, storage in artificial saliva after 10 minutes and 7 days, and citric acid challenge for 3 minutes. Data were analysed with a repeated measures ANOVA test. Dentine discs (n=12) were used for SEM/EDX analyses to acquire data on morphological changes on dentine surface and its mineral content after different stages of treatment. Results. Desensitizing agents' application on the demineralized dentine discs exhibited significant reduction of permeability compared to its maximum acid permeability values. Mp-Mh oxalate showed a significant reduction in dentine permeability (p<0.05) when compared to RMGI XT VAR and LIQ SiO2. On SEM/EDX analysis, all the agents formed mineral precipitates that occluded the dentine tubules. Conclusions. 2.7% wt. monopotassium-monohydrogen oxalate was significantly effective in reducing dentine permeability compared to RMGI XT VAR and LIQ SiO2.

Item Type: Article
Funders: UNSPECIFIED
Uncontrolled Keywords: Desensitizing agents; In vitro effectiveness
Subjects: R Medicine > RK Dentistry
Divisions: Faculty of Dentistry
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 25 Feb 2022 03:02
Last Modified: 25 Feb 2022 03:02
URI: http://eprints.um.edu.my/id/eprint/26389

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