Effect of reconstruction parameters on cone beam CT trabecular bone microstructure quantification in sheep

Muhammad, Aso Muhammad Ali and Ibrahim, Norliza and Ahmad, Rohana and Asif, Muhammad Khan and Radzi, Zamri and Zaini, Zuraiza Mohamad and Razak, Hairil Rashmizal Abdul (2020) Effect of reconstruction parameters on cone beam CT trabecular bone microstructure quantification in sheep. BMC Oral Health, 20. p. 48. ISSN 1472-6831, DOI https://doi.org/10.1186/s12903-020-1035-7.

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Abstract

Background Cone Beam Computed Tomography (CBCT) is a reliable radiographic modality to assess trabecular bone microarchitecture. The aim of this study was to determine the effect of CBCT image reconstruction parameters, namely, the threshold value and reconstruction voxel size, on trabecular bone microstructure assessment. Methods Five sectioned maxilla of adult Dorper male sheep were scanned using a CBCT system with a resolution of 76 μm3 (Kodak 9000). The CBCT images were reconstructed using different reconstruction parameters and analysed. The effect of reconstruction voxel size (76, 100 and 200 μm3) and threshold values (±15% from the global threshold value) on trabecular bone microstructure measurement was assessed using image analysis software (CT analyser version 1.15). Results There was no significant difference in trabecular bone microstructure measurement between the reconstruction voxel sizes, but a significant difference (Tb.N = 0.03, Tb.Sp = 0.04, Tb.Th = 0.01, BV/TV = 0.00) was apparent when the global threshold value was decreased by 15%. Conclusions Trabecular bone microstructure measurements are not compromised by changing the CBCT reconstruction voxel size. However, measurements can be affected when applying a threshold value of less than 15% of the recommended global value.

Item Type: Article
Funders: Universiti Teknologi Mara (UiTM), Malaysia Higher Education Fundamental Research Grant Scheme (FRGS/1/2015/SKK14/UITM/02/2), High Impact Research MoE Grant (UM.C/625/1/HIR/MOHE/DENT/21) by Ministry of Higher Education, Malaysia
Uncontrolled Keywords: CBCT; Trabecular bone; Reconstruction parameters; Threshold value; microcomputed tomography; voxel size; accuracy; Dentistry, Oral Surgery & Medicine
Subjects: R Medicine > RK Dentistry > Oral surgery
R Medicine > RK Dentistry > Practice of dentistry. Dental economics
Divisions: Faculty of Dentistry
Depositing User: Mr Ahmad Azwan Azman
Date Deposited: 13 Jul 2020 01:48
Last Modified: 13 Jul 2020 01:48
URI: http://eprints.um.edu.my/id/eprint/25018

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