Eow, G.I. and Kim, L.H. and Peh, S.C. (2006) The pattern of CD15, CD30 and Bcl-2 expression in diffuse large B-cell lymphoma. Medical Journal of Malaysia, 61 (4). pp. 416-421. ISSN 0300-5283,
Full text not available from this repository.Abstract
Diffuse large B-cell lymphoma (DLBCL) is a heterogenous entity. The pattern of CD15, CD30 and Bcl-2 expression is not well documented, especially in local population. We investigated 67 consecutive cases of DLBCL by immunohistochemistry on paraffin-embedded tissue. The male to female ratio was 1.2:1 with median age of 55 years, and more common nodal than extranodal in presentation. Only 3 of 67 cases expressed CD15. In addition, three cases showed weak membrane staining for CD30. Only one of these three cases was noted to have co-expression of CD15 and with occasional tumour cells showing weak CD30 expression. Bcl-2 protein was expressed in 43 of 67 (64%), more frequently in nodal than in extranodal tumours. In conclusion, CD15 and CD30 expressions are infrequent in DLBCL, and co-expression is rare. Bcl-2 protein expression is common in DLBCL.
| Item Type: | Article |
|---|---|
| Funders: | UNSPECIFIED |
| Uncontrolled Keywords: | Diffuse large B-cell lymphoma; CD15; CD30; Bcl-2 |
| Subjects: | R Medicine |
| Divisions: | Faculty of Medicine |
| Depositing User: | Mr Jasny Razali |
| Date Deposited: | 22 Mar 2021 04:06 |
| Last Modified: | 22 Mar 2021 04:06 |
| URI: | http://eprints.um.edu.my/id/eprint/24549 |
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