Yee, Anne and Loh, Huai Seng and Loh, Huai Heng and Riahi, Shahrzad and Ng, Chong Guan and Sulaiman, Ahmad Hatim (2019) A comparison of sexual desire in opiate-dependent men receiving methadone and buprenorphine maintenance treatment. Annals of General Psychiatry, 18 (1). p. 25. ISSN 1744-859X, DOI https://doi.org/10.1186/s12991-019-0249-z.
Full text not available from this repository.Abstract
Background: Methadone is an effective therapy for opiate dependence. However, one of the commonest side effects is sexual dysfunction among male patients. Buprenorphine is an alternative to methadone. This study aimed to compare sexual desire among opiate-dependent male patients on buprenorphine (BMT) and methadone maintenance therapy (MMT). Methods: This cross-sectional study involved 126 male opiate-dependent patient who were tested for total testosterone (TT) and prolactin levels, and were interviewed and completed the Sexual Desire Inventory-2 (SDI-2), Malay language of International Index of Erectile Function (Mal-IIEF-15) and the Malay version of the self-rated Montgomery-Asberg Depression Rating Scale (MADRS-BM) questionnaires. Results: There were 95 (75.4%) patients on MMT and 31 (24.6%) on BMT. Patients on MMT scored significantly lower in the sexual desire domain (Mal-IIEF-15 scores) (p < 0.01), dyadic sexual desire (p = 0.04) and TT plasma level (p < 0.01) when compared to BMT group after controlling all the confounders. Conclusions: Patients on MMT are associated with lower sexual desire when compared with patients on BMT. Smoking may further lower testosterone and, hence, sexual desire in those already on methadone. © 2019 The Author(s).
| Item Type: | Article |
|---|---|
| Funders: | UNSPECIFIED |
| Uncontrolled Keywords: | Buprenorphine; Methadone; Sexual desire; Sexual dysfunction; Smoking |
| Subjects: | R Medicine |
| Divisions: | Faculty of Medicine |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 27 Nov 2019 03:37 |
| Last Modified: | 27 Nov 2019 03:37 |
| URI: | http://eprints.um.edu.my/id/eprint/23105 |
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