Lim, Levinia and Ng, Tze Pin and Ong, Anam Paulus and Tan, Maw Pin and Cenina, Alvin Rae and Gao, Qi and Ng, Adeline and Kandiah, Nagaendran (2018) A novel language-neutral Visual Cognitive Assessment Test (VCAT): validation in four Southeast Asian countries. Alzheimer's Research & Therapy, 10 (1). p. 6. ISSN 1758-9193, DOI https://doi.org/10.1186/s13195-017-0333-z.
Full text not available from this repository.Abstract
Background: Cognitive screeners are imperative for early diagnosis of dementia. The Visual Cognitive Assessment Test (VCAT) is a language-neutral, visual-based test which has proven useful for a multilingual population in a single-center study. However, its performance utility is unknown in a wider and more diverse Southeast Asian cohort. Methods: We recruited 164 healthy controls (HC) and 120 cognitively impaired (CI) subjects- 47 mild cognitive impairment (MCI) and 73 mild Alzheimer's disease (AD) dementia participants, from four countries between January 2015 and August 2016 to determine the usefulness of a single version of the VCAT, without translation or adaptation, in a multinational, multilingual population. The VCAT was administered along with established cognitive evaluation. Results: The VCAT, without local translation or adaptation, was effective in discriminating between HC and CI subjects (MCI and mild AD dementia). Mean (SD) VCAT scores for HC and CI subjects were 22.48 (3.50) and 14.17 (5.05) respectively. Areas under the curve for Montreal Cognitive Assessment (0.916, 95% CI 0.884-0.948) and the VCAT (0.905, 95% CI 0.870-0.940) in discriminating between HCs and CIs were comparable. The multiple languages used to administer VCAT in four countries did not significantly influence test scores. Conclusions: The VCAT without the need for language translation or cultural adaptation showed satisfactory discriminative ability and was effective in a multinational, multilingual Southeast Asian population.
| Item Type: | Article |
|---|---|
| Funders: | UNSPECIFIED |
| Uncontrolled Keywords: | Alzheimer's disease; Cognitive test; Dementia; Mild cognitive impairment; Screening tool |
| Subjects: | R Medicine |
| Divisions: | Faculty of Medicine |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 31 May 2019 03:56 |
| Last Modified: | 31 May 2019 03:56 |
| URI: | http://eprints.um.edu.my/id/eprint/21445 |
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