Pakalapati, Harshini and Arumugasamy, Senthil Kumar and Jewaratnam, Jegalakshimi and Wong, Yong Jie and Khalid, Mohammad (2018) Parametric optimization of polycaprolactone synthesis catalysed by Candida antarctica lipase B using response surface methodology. Biopolymers, 109 (12). e23240. ISSN 0006-3525, DOI https://doi.org/10.1002/bip.23240.
Full text not available from this repository.Abstract
A statistical approach with D-optimal design was used to optimize the process parameters for polycaprolactone (PCL) synthesis. The variables selected were temperature (50°C-110°C), time (1-7 h), mixing speed (50-500 rpm) and monomer/solvent ratio (1:1-1:6). Molecular weight was chosen as response and was determined using matrix-assisted laser desorption/ionization time of flight (MALDI TOF). Using the D-optimal method in design of experiments, the interactions between parameters and responses were analysed and validated. The results show a good agreement with a minimum error between the actual and predicted values.
| Item Type: | Article |
|---|---|
| Funders: | UNSPECIFIED |
| Uncontrolled Keywords: | Candida Antarctica lipase B; D-optimal method; design of experiment; enzymatic polymerization; optimization; polycaprolactone |
| Subjects: | T Technology > TP Chemical technology |
| Divisions: | Faculty of Engineering |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 24 Apr 2019 03:46 |
| Last Modified: | 24 Apr 2019 03:46 |
| URI: | http://eprints.um.edu.my/id/eprint/21049 |
Actions (login required)
 |
View Item |
