Neolamarckines A and B, New Indole Alkaloids from Neolamarckia cadamba.

Qureshi, Ahmad Kaleem and Mukhtar, Mat Ropi and Hirasawa, Yusuke and Hosoya, Takahiro and Nugroho, Alfarius Eko and Morita, Hiroshi and Shirota, Osamu and Mohamad, Khalit and A. Hadi, A. Hamid and Litaudon, M. and Awang, Khalijah (2011) Neolamarckines A and B, New Indole Alkaloids from Neolamarckia cadamba. Chemical & Pharmaceutical Bulletin, 59 (2). pp. 291-3. ISSN 1347-5223, DOI 21297315.

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Official URL: http://www.jstage.jst.go.jp/article/cpb/59/2/59_29...

Abstract

Two new indole alkaloids, neolamarckines A and B (1, 2) were isolated from the leaves of Neolamarckia cadamba (Rubiaceae). Structural elucidation of 1 and 2 was performed by combination of 2D-NMR and circular dichroism (CD) spectra, and chemical correlations. Neolamarckine A (1) showed inhibition of inducible nitric oxide synthase (iNOS) dose dependently.

Item Type: Article
Funders: UNSPECIFIED
Uncontrolled Keywords: neolamarckine; indole; Neolamarckia cadamba; Rubiaceae; inducible nitric oxide synthase activity
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Faculty of Science > Department of Chemistry
Depositing User: Zanaria Saupi Udin
Date Deposited: 26 Feb 2011 07:19
Last Modified: 02 Sep 2021 03:37
URI: http://eprints.um.edu.my/id/eprint/175

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