Bisleuconothine A, an eburnane-aspidosperma bisindole alkaloid from Leuconotis griffithii

Hirasawa, Y. and Shoji, T. and Arai, T. and Nugroho, A.E. and Deguchi, J. and Hosoya, T. and Uchiyama, N. and Goda, Y. and Awang, K. and Hadi, A.H.A. and Shiro, M. and Morita, H. (2010) Bisleuconothine A, an eburnane-aspidosperma bisindole alkaloid from Leuconotis griffithii. Bioorganic & Medicinal Chemistry Letters, 20 (6). pp. 2021-2024.

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Abstract

A new bisindole alkaloid, bisleuconothine A(1) consisting of an eburnane-aspidosperma type skeleton, was isolated from the bark of Leuconotis griffithii. The structure including absolute stereochemistry was elucidated on the basis of 2D NMR data and X-ray analysis. Bisleuconothine A(1) showed cell growth inhibitory activity against various human cancer cell lines. (C) 2010 Elsevier Ltd. All rights reserved.

Item Type: Article
Funders: UNSPECIFIED
Subjects: Q Science > Q Science (General)
Depositing User: MR Faizal II H
Date Deposited: 01 Dec 2015 00:38
Last Modified: 01 Dec 2015 00:38
URI: http://eprints.um.edu.my/id/eprint/14977

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