Hwa, W.E. and Subramaniam, G. and Mansor, Marzida and Yan, O.S. and Anbazhagan, D. and Devi, S.S. (2010) Iron regulated outer membrane proteins (IROMPs) as potential targets against carbapenem-resistant Acinetobacter spp. isolated from a Medical Centre in Malaysia. Indian Journal of Medical Research, 131. pp. 578-583. ISSN 0971-5916, DOI PMID: 20424311.
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Official URL: http://www.ijmr.org.in/temp/IndianJMedRes1314578-1...
Abstract
In this study, a 29-kDa OMP has been identified to be the major outer membrane protein in A. baumannii / calcoaceticus and loss of this porin and overexpression of IROMPs have contributed to carbapenem resistance. Polyclonal antibodies raised against IROMPs may have a role in antimicrobial therapy in these isolates.
| Item Type: | Article |
|---|---|
| Funders: | UNSPECIFIED |
| Additional Information: | Department of Medical Microbiology, Faculty of Medicine, University Malaya Kuala Lumpur, Malaysia. |
| Uncontrolled Keywords: | Acinetobacter spp.; imipenem; iron regulated outer membrane protein (IROMPs); meropenem; multiresistant; outer membrane protein (OMP); SDS-PAGE |
| Subjects: | R Medicine |
| Divisions: | Faculty of Medicine |
| Depositing User: | Mr. Faizal Hamzah |
| Date Deposited: | 17 May 2011 02:04 |
| Last Modified: | 04 Apr 2019 08:25 |
| URI: | http://eprints.um.edu.my/id/eprint/1231 |
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