Ngoi, S.T. and Thong, Kwai Lin (2013) Molecular characterization showed limited genetic diversity among Salmonella Enteritidis isolated from humans and animals in Malaysia. Diagnostic Microbiology and Infectious Disease, 77 (2012). pp. 304-311.
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Abstract
Salmonella enterica serovar Enteritidis (S. Enteritidis) is the most common causative agent of non-typhoidal salmonellosis in Malaysia. We aimed to characterize S. Enteritidis isolated from humans and animals by analyzing their antimicrobial resistance profiles and genotypes. A total of 111 strains were characterized using multiple-locus variable-number tandem repeat analysis, pulsed-field gel electrophoresis, and antimicrobial susceptibility testing. Both typing methods revealed that genetically similar S.Enteritidis strains had persisted among human and animal populations within the period of study (2003–2008). Only 39% of the strains were multi-drug resistant (i.e., resistant to 3 or more classes of antimicrobial agents), with a majority (73%) of these in low-risk phase (multiple antibiotic resistant index b0.20). Limited genetic diversity among clinical and zoonotic S. Enteritidis suggested that animals are possible sources of human salmonellosis. The degree of multi-drug resistance among the strains was generally low during the study period.
| Item Type: | Article |
|---|---|
| Funders: | UNSPECIFIED |
| Subjects: | Q Science > QR Microbiology |
| Divisions: | Faculty of Science > Institute of Biological Sciences |
| Depositing User: | Prof. Dr Kwai Lin Thong |
| Date Deposited: | 25 Jun 2014 06:53 |
| Last Modified: | 15 Oct 2018 05:26 |
| URI: | http://eprints.um.edu.my/id/eprint/10648 |
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