Atroosh, W.M. and Al-Mekhlafi, H.M. and Mahdy, M.A.K. and Surin, J. (2012) The detection of pfcrt and pfmdr1 point mutations as molecular markers of chloroquine drug resistance, Pahang, Malaysia. Malaria Journal.
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Abstract
Malaria is still a public health problem in Malaysia with chloroquine (CQ) being the first-line drug in the treatment policy of uncomplicated malaria. There is a scarcity in information about the magnitude of Plasmodium falciparum CQ resistance. This study aims to investigate the presence of single point mutations in the P. falciparum chloroquine-resistance transporter gene (pfcrt) at codons 76, 271, 326, 356 and 371 and in P. falciparum multi-drug resistance-1 gene (pfmdr1) at codons 86 and 1246, as molecular markers of CQ resistance
| Item Type: | Article |
|---|---|
| Funders: | UNSPECIFIED |
| Uncontrolled Keywords: | Malaria, Plasmodium falciparum, P. falciparum |
| Subjects: | Q Science > Q Science (General) R Medicine > R Medicine (General) |
| Divisions: | Faculty of Medicine |
| Depositing User: | Ms. Nur Azzura Azzahra Jaafar |
| Date Deposited: | 13 Jun 2014 01:21 |
| Last Modified: | 13 Jun 2014 01:21 |
| URI: | http://eprints.um.edu.my/id/eprint/10546 |
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