Kam, T.S. and Ku, W.F. and Tan, S.J. and Low, Y.Y. and Komiyama, K. (2011) Angustilobine and andranginine type indole alkaloids and an uleine–secovallesamine bisindole alkaloid from Alstonia angustiloba. Phytochemistry, 72. pp. 2212-2218. ISSN 0031-9422, DOI https://doi.org/10.1016/j.phytochem.2011.08.001.
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Abstract
A total of 20 alkaloids were isolated from the leaf and stem-bark extracts of Alstonia angustiloba, of which two are hitherto unknown. One is an alkaloid of the angustilobine type (angustilobine C), while the other is a bisindole alkaloid angustiphylline, derived from the union of uleine and secovallesamine moieties. The structures of these alkaloids were established using NMR and MS analysis. Angustilobine C showed moderate cytotoxicity towards KB cells.
| Item Type: | Article |
|---|---|
| Funders: | UNSPECIFIED |
| Additional Information: | Department of Chemistry, University of Malaya |
| Uncontrolled Keywords: | Apocynaceae; Alstonia angustiloba; Alkaloids; Bisindole; NMR; Cytotoxicity. |
| Subjects: | Q Science > QD Chemistry |
| Divisions: | Faculty of Science > Department of Chemistry |
| Depositing User: | Ms. Suhaila Syakila Alby |
| Date Deposited: | 15 Oct 2014 01:52 |
| Last Modified: | 15 Oct 2014 01:52 |
| URI: | http://eprints.um.edu.my/id/eprint/10391 |
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