Kam, T.S. and Nge, C.E. and Gan, C.Y. and Low, Y.Y. and Thomas, N.F. (2013) Voatinggine and tabertinggine, pentacyclic indole alkaloids derived from an iboga precursor via a common cleavamine-type intermediate. Organic Letters, 15 (18). pp. 4774-4777. ISSN 1523-7060, DOI https://doi.org/10.1021/ol4021404.
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Abstract
Two new indole alkaloids, voatinggine (1) and tabertinggine (2), which are characterized by previously unencountered natural product skeletons,were isolated from a Malayan Tabernaemontana species. The structures and absolute configuration of these alkaloids were determined using NMR and MS analysis, and X-ray diffraction analysis. A possible biogenetic pathway to these novel alkaloids from an iboga precursor, and via a common cleavamine-type intermediate, is presented.
| Item Type: | Article |
|---|---|
| Funders: | UNSPECIFIED |
| Additional Information: | Department of Chemistry, Faculty of Science, University of Malaya |
| Uncontrolled Keywords: | Tabernaemontana; Alkaloids; Hexacyclic indole conolutinine; Aspidosperma. |
| Subjects: | Q Science > QD Chemistry |
| Divisions: | Faculty of Science > Department of Chemistry |
| Depositing User: | Ms. Suhaila Syakila Alby |
| Date Deposited: | 31 Oct 2014 03:00 |
| Last Modified: | 31 Oct 2014 03:00 |
| URI: | http://eprints.um.edu.my/id/eprint/10384 |
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