Kee, Chia Ching and Ng, Kelvin and Ang, Bee Chin and Metselaar, Hendrik Simon Cornelis (2023) Synthesis, characterization and in-vitro biocompatibility of electrophoretic deposited europium-doped calcium silicate on titanium substrate. Journal of the European Ceramic Society, 43 (3). pp. 1189-1204. ISSN 0955-2219, DOI https://doi.org/10.1016/j.jeurceramsoc.2022.10.048.
Full text not available from this repository.Abstract
Europium (Eu) has attracted attention to be incorporated as biologically active ions to achieve different biological and functional properties of biomaterials. In this study, calcium silicate (CS) coatings doped with different amount of Eu (up to 10 mol%) were successfully formed on titanium substrates via electrophoretic deposition. A low amount of Eu (2.5 mol%) gave a relatively denser coating and improved coating adhesion strength (similar to 3.3 N). All Eu-CS coatings provided good apatite forming ability, yet lower degradation rate, as compared to CS coating. Moreover, it was observed that the human fetal osteoblast (hFOB) cells could attach and proliferate on all Eu-CS coatings, suggesting their biocompatible nature. Eu2.5CS not only showed comparable cell proliferation with CS, but also enhanced the osteogenic activity of the CS coating. All results suggested that Eu2.5CS coatings are promising coating materials for biomedical implants, particularly bone tissue engineering applications.
| Item Type: | Article |
|---|---|
| Funders: | Ministry of Education, Malaysia, Fundamental Research Grant Scheme (FRGS) (FP048-2019A), Universiti Malaya of Malaysia through the Postgraduate Research Grant (PG114-2015A), MOHE via MyBrain15-MyPhD program |
| Uncontrolled Keywords: | Calcium silicate; Europium; Coating; Electrophoretic deposition; Biocompatibility |
| Subjects: | T Technology > TA Engineering (General). Civil engineering (General) T Technology > TJ Mechanical engineering and machinery T Technology > TP Chemical technology |
| Divisions: | Faculty of Engineering Faculty of Engineering > Department of Biomedical Engineering Faculty of Engineering > Department of Chemical Engineering Faculty of Engineering > Department of Mechanical Engineering |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 16 Jul 2025 03:49 |
| Last Modified: | 16 Jul 2025 03:49 |
| URI: | http://eprints.um.edu.my/id/eprint/50996 |
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