Hiba, Ibrahim Huzyan and Koh, Jin Kwei and Lai, Chin Wei and Mousavi, Seyyed Mojtaba and Badruddin, Irfan Anjum and Hussien, Mohamed and Wong, Jest Phia (2024) Polyrhodanine-based nanomaterials for biomedical applications: A review. Heliyon, 10 (7). e28902. ISSN 2405-8440, DOI https://doi.org/10.1016/j.heliyon.2024.e28902.
Full text not available from this repository.Abstract
Rhodanine is a heterocyclic organic compound that has been investigated for its potential biomedical applications, particularly in drug discovery. Rhodanine derivatives have been examined as the medication options for numerous illnesses, including cancer, inflammation, and infectious diseases. Some rhodanine derivatives have also shown promising activity against drug -resistant strains of bacteria and viruses. One of these derivatives is polyrhodanine (PR), a conducting polymer that has gained attention for its biomedical properties. This review article summarises the latest advancements in creating biomaterials based on PR for biosensing, antimicrobial treatments, and anticancer therapies. The distinctive characteristics of PR, such as biocompatibility, biodegradability, and good conductivity, render it an attractive candidate for these applications. The article also explores obstacles and potential future paths for advancing biomaterials made with PR, including synthesis modifications, characterisation techniques, and in vivo evaluation of biocompatibility and efficacy. Overall, as an emerging research topic, this review emphasises the potential of PR as a promising biomaterial for various biomedical applications and provides insights into the contemporary state of research and prospective directions for investigation.
| Item Type: | Article |
|---|---|
| Funders: | Universiti Malaya Research Excellence Grant (UMREG), Global Collaborative Programme - SATU Joint Research Scheme (ST008-2023), Harper Elite Sdn. Bhd. (PV090-2023), King Khalid University King Saud University (RGP.2/415/44) |
| Subjects: | Q Science > Q Science (General) T Technology > T Technology (General) |
| Divisions: | Deputy Vice Chancellor (Research & Innovation) Office > Nanotechnology & Catalysis Research Centre |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 09 Jan 2025 02:11 |
| Last Modified: | 09 Jan 2025 02:11 |
| URI: | http://eprints.um.edu.my/id/eprint/46993 |
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