Ahmed, Syed Rahin and Sherazee, Masoomeh and Das, Poushali and Shalauddin, Md and Akhter, Shamima and Basirun, Wan Jefrey and Srinivasan, Seshasai and Rajabzadeh, Amin Reza (2024) Electrochemical assisted enhanced nanozymatic activity of functionalized borophene for H2O2 and tetracycline detection. Biosensors & bioelectronics, 246. ISSN 0956-5663, DOI https://doi.org/10.1016/j.bios.2023.115857.
Full text not available from this repository.Abstract
This study unveils the electrochemically-enhanced nanozymatic activity exhibited by borophene during the reaction of 3,3 `,5,5 `-tetramethylbenzidine (TMB) and H2O2. Herein, the surface of the pristine borophene was first modified with the addition of thiocyanate groups to improve hydroxyl radical (center dot OH) scavenging activity. Then, the oxidation reaction of TMB was accelerated under applied electrochemical potential. Both factors significantly improved the detection limit and drastically decreased the detection time. DPPH testing revealed that the radical scavenging nature of borophene was more than 70%, boosting its catalytic activity. In the presence of H2O2, borophene catalyzed the oxidation of TMB and produced a blue-colored solution that was linearly correlated with the concentration of H2O2 and allowed for the detection of H2O2 up to 38 nM. The present finding was further extended to nanozymatic detection of tetracyclines (TCs) using a target-specific aptamer, and the results were colorimetrically quantifiable up to 1 mu M with a LOD value of 150 nM. Moreover, transferring the principles of the discussed detection method to form a portable and disposable paper-based system enabled the quantification of TCs up to 0.2 mu M. All the sensing experiments in this study indicate that the nanozymatic activity of borophene has significantly improved under electrochemical potential compared to conventional nanozyme-based colorimetric detection. Hence, the present discovery of electrochemicallyenhanced nanozymatic activity would be promising for various sensitive and time-dependent colorimetric sensor development initiatives in the future.
| Item Type: | Article |
|---|---|
| Funders: | SCN-borophene/GCE demonstrates a very fast OER, Natural Sciences and Engineering Research Council of Canada [Grant No: PPSI-2020-CLUSTER-IDIG04, RGPIN-2015-04737, RGPIN-2019-07246], Universiti Malaya |
| Uncontrolled Keywords: | Borophene; Nanozyme; Tetracyclines; Paper-based assay; Colorimetric detection |
| Subjects: | Q Science > QD Chemistry T Technology > T Technology (General) |
| Divisions: | Faculty of Engineering > Biomedical Engineering Department Faculty of Science > Department of Chemistry |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 17 Oct 2024 04:23 |
| Last Modified: | 17 Oct 2024 04:23 |
| URI: | http://eprints.um.edu.my/id/eprint/45966 |
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