Histologic and histomorphometric evaluation of peri-implant bone subjected to immediate loading: an experimental study with Macaca fascicularis

Romanos, G.E.; Toh, C.G.; Siar, C.H.; Swaminathan, D.; Ong, A.H. (2002) Histologic and histomorphometric evaluation of peri-implant bone subjected to immediate loading: an experimental study with Macaca fascicularis. International Journal of Oral & Maxillofacial Implants, 17 (1). pp. 44-51. ISSN 0882-2786

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    Abstract

    Purpose: Immediately loaded splinted implants can become osseointegrated when they are placed in the anterior part of the mandible. The concept of immediate loading has not been well examined in the posterior mandible. The aim of this study was to evaluate the hard tissue reactions around immediately loaded implants placed in the posterior mandible in the monkey model. Materials and Methods: Six adult M. fascicularis monkeys were used in this study. Thirty-six Ankylos implants (Degussa Dental, Hanau-Wolfgang, Germany) were placed after extraction of the second premolar, first, and second molar teeth and complete healing of the sockets. Control (C) group implants were placed and, after osseointegration, were loaded for 1 month using temporary acrylic resin prostheses and later for 2 months using splinted metal crowns. In the contralateral region of the mandible, test (T) group implants were placed and loaded immediately with the same sequence as carried out for the C implants. After sacrifice of the animals, specimens were examined histologically and evaluated histomorphometrically. Results: All implants were osseointegrated. Compact, cortical bone In contact with the implant surface without any gaps or connective tissue formation was demonstrated. Discussion: Histomorphometric findings of the bone-implant-contacts showed no significant differences between the T and C group implants. Peri-implant mineralized bone areas presented statistically significant differences and showed a higher density of bone between the threads of immediately loaded implants (P < .05). Conclusions: Immediately loaded splinted implants in the posterior mandible can become osseointegrated with a hard tissue peri-implant response similar to that of delayed loaded implants. Moreover, immediate loading seems to increase the ossification of the alveolar bone around endosseous implants.

    Item Type: Article
    Creators:
    1. Romanos, G.E.
    2. Toh, C.G.
    3. Siar, C.H.
    4. Swaminathan, D.
    5. Ong, A.H.
    Journal or Publication Title: International Journal of Oral & Maxillofacial Implants
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    Uncontrolled Keywords: Bone immediate loading implant monkey posterior mandible dental implants titanium implants soft-tissues interface dogs prostheses
    Subjects: R Medicine > RK Dentistry
    Divisions: Faculty of Dentistry > Dept of Oral Pathology & Oral Medicine & Periodontology
    Depositing User: Ms Nursyafiqah Abd Malek
    Date Deposited: 10 Jan 2013 08:16
    Last Modified: 10 Jan 2013 08:16
    URI: http://eprints.um.edu.my/id/eprint/4314

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