Green synthesis of antibacterial nanocomposite of silver nanoparticle-doped hydroxyapatite utilizing Curcuma longa leaf extract and land snail (Achatina fulica) shell waste

Fatimah, Is and Hidayat, Habibi and Purwiandono, Gani and Khoirunisa, Khoirunisa and Zahra, Hasna Azizah and Audita, Rahmania and Sagadevan, Suresh (2022) Green synthesis of antibacterial nanocomposite of silver nanoparticle-doped hydroxyapatite utilizing Curcuma longa leaf extract and land snail (Achatina fulica) shell waste. Journal of Functional Biomaterials, 13 (2). ISSN 2079-4983, DOI https://doi.org/10.3390/jfb13020084.

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Abstract

Preparation of green synthesized silver nanoparticle (AgNPs)-doped hydroxyapatite (Ag/HA) utilizing Curcuma longa leaf extract and land snail (Achatina fulica) shell waste was performed. Physicochemical characteristics and antibacterial activity of Ag/HA composite as a function of Ag content was studied. Instrumental analysis such as XRD, SEM-EDX, TEM, and XPS were employed to characterize the nanocomposites. The physicochemical study revealed the maintained porous structure of HA after Ag immobilization, and from TEM analyses, it was found that the distributed spherical particles are associated with the dispersed Ag and have a particle diameter of around 5-25 nm. Antibacterial activity of the nanocomposite was evaluated against Escherichia coli, Staphylococcus aureus, Kliebsiella pneumonia, and Streptococcus pyogenes. The results showed that the varied Ag content (1.0; 1.6; and 2.4% wt) influenced the nanoparticle distribution in the nanocomposite and enhanced the antibacterial feature.

Item Type: Article
Funders: Universitas Islam Indonesia (Grant No: 001/Dir/DPPM/70/Pen)
Uncontrolled Keywords: Hydroxyapatite; Silver nanoparticles; Antibacterial nanocomposite
Subjects: Q Science > Q Science (General)
T Technology > T Technology (General)
Divisions: Nanotechnology & Catalysis Research Centre
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 19 Oct 2023 05:02
Last Modified: 19 Oct 2023 05:02
URI: http://eprints.um.edu.my/id/eprint/41951

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