Rajendran, Archana and Sagadevan, Suresh and Lett, Jayasingh Anita and Kaliaraj, Gobi Saravanan and Fatimah, Is and Mohammad, Faruq and Al-Lohedan, Hamad A. and Alshahateet, Solhe F. and Podder, Jiban (2021) Synthesis, growth, supramolecularity and antibacterial efficacy of 3,4-dimethoxybenzoic acid single crystals. Chemical Physics Letters, 764. ISSN 0009-2614, DOI https://doi.org/10.1016/j.cplett.2020.138269.
Full text not available from this repository.Abstract
In this paper, we have investigated the antibacterial potentials of organic single crystals, 3,4-dimethoxybenzoic acid (DMBA) grown by the slow evaporation solution growth technique. The crystallinity and structural orientation of as-grown DMBA compound was thoroughly studied using single-crystal X-ray diffraction and powder Xray diffraction (XRD) and found to be a triclinic crystal system with P1 space group. The Fourier transform infrared spectroscopy was used to understand the nature of bonding and functionalization, while the UV-Vis spectroscopic analysis provided the linear optical properties at the lower cutoff wavelength of 350 nm and transparency of 87%. Also, the photoluminescence spectrum shows the ultraviolet emission of the DMBA single crystal. Further, the antibacterial efficacy of DMBA crystals is investigated by means of percentage (%) inhibition and zone of inhibition (ZoI) against the two different bacterial stains of Klebsiella pneumoniae and Staphylococcus aureus. The results confirmed that the DMBA compound has higher activity against Staphylococcus aureus growth (75% inhibition efficiency and 5 mm ZoI at 100 mu g/mL) than that of Klebsiella pneumoniae (55% inhibition and 2 mm ZoI at 100 mu g/mL) and thereby providing evidence for the potential role of the DMBA compound in future medicinal drugs.
| Item Type: | Article |
|---|---|
| Funders: | Universiti Malaya[RU0012020], King Saud University |
| Uncontrolled Keywords: | 3, 4-dimethoxy benzoic acid;Slow evaporation;Antibacterial activity;Powder X-ray diffraction;Single crystals |
| Subjects: | Q Science > QC Physics Q Science > QD Chemistry T Technology > T Technology (General) |
| Divisions: | Deputy Vice Chancellor (Research & Innovation) Office > Nanotechnology & Catalysis Research Centre |
| Depositing User: | Ms Zaharah Ramly |
| Date Deposited: | 08 Sep 2022 07:49 |
| Last Modified: | 08 Sep 2022 07:49 |
| URI: | http://eprints.um.edu.my/id/eprint/34252 |
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