Kaliaraj, Gobi Saravanan and Thukkaram, Sudhakar and Alagarsamy, Karthik and Kirubaharan, A. M. Kamalan and Paul, Likhitha Kiliyelathu and Abraham, Linta and Vishwakarma, Vinita and Sagadevan, Suresh (2021) Silver-calcia stabilized zirconia nanocomposite coated medical grade stainless steel as potential bioimplants. Surfaces and Interfaces, 24. ISSN 2468-0230, DOI https://doi.org/10.1016/j.surfin.2021.101086.
Full text not available from this repository.Abstract
Surface tailoring of bioimplants is a prerequisite for reducing inflammation and improving durability. In this work, novel calcia stabilized zirconia (CaSZ) and silver-CaSZ nanocomposite coatings were developed on medical grade stainless steel (316L SS). We analyzed their microstructure, mechanical, biological and corrosion resistance performance. Ag-CaSZ nanocomposite coating effectively arrested Pseudomonas aeruginosa bacterial growth without compromising its biocompatibility. Hemolytic behavior was studied and the results confirmed that the samples expressed hemocompatible nature. Further, CaSZ and Ag-CaSZ nanocomposite coatings enhanced osteoblast-like cells (MG-63) adhesion with improved calcite precipitation (biomineralization) using Alizarin red-based assay (ARS). Finally, electrochemical bio-corrosion was performed with Artificial Blood Plasma (ABP) solution. The chemical inertness of ceramics and the formation of the passive layer could enhance corrosion resistance.
| Item Type: | Article |
|---|---|
| Funders: | Department of Biotechnology (DBT) India[BT/PR14718/MED/32/434/2015] |
| Uncontrolled Keywords: | E-beam evaporation;CaSZ coating;Protein adhesion;Corrosion; Biomineralization |
| Subjects: | Q Science > QC Physics Q Science > QD Chemistry |
| Divisions: | Deputy Vice Chancellor (Research & Innovation) Office > Nanotechnology & Catalysis Research Centre |
| Depositing User: | Ms Zaharah Ramly |
| Date Deposited: | 18 Jul 2022 07:36 |
| Last Modified: | 18 Jul 2022 07:36 |
| URI: | http://eprints.um.edu.my/id/eprint/34095 |
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