Hong, Yun Soo and Jung, Kyung Uk and Rampal, Sanjay and Zhao, Di and Guallar, Eliseo and Ryu, Seungho and Chang, Yoosoo and Kim, Hyung Ook and Kim, Hungdai and Chun, Ho-Kyung and Sohn, Chong Il and Shin, Hocheol and Cho, Juhee (2022) Risk factors for hemorrhoidal disease among healthy young and middle-aged Korean adults. Scientific Reports, 12 (1). ISSN 2045-2322, DOI https://doi.org/10.1038/s41598-021-03838-z.
Full text not available from this repository.Abstract
Hemorrhoidal disease is a highly prevalent anorectal condition causing substantial discomfort, disability, and decreased quality of life. Evidence on preventable risk factors for hemorrhoidal disease is limited. We conducted a cross-sectional study of 194,620 healthy men and women who completed a health screening exam including colonoscopy in 2011-2017. We evaluated potential risk factors of hemorrhoidal disease, including lifestyle factors, medical history, birth history, gastrointestinal symptoms, and anthropometric measurements. The prevalence of hemorrhoidal disease was 16.6%, and it was higher in females than in males (17.2 vs. 16.3%; P<0.001). Compared to men, the prevalence of hemorrhoidal disease was higher in parous women (adjusted odds ratio OR] 1.06; 95% confidence interval CI] 1.02-1.10), and lower in nulliparous women (adjusted OR 0.92; 95% CI 0.86-0.98). In the adjusted analyses, older age, female sex, smoking, overweight, and being hypertensive were independently associated with the presence of hemorrhoidal disease. The prevalence of hemorrhoidal disease was positively associated with body mass index and waist circumference in parous women. The prevalence of hemorrhoidal disease was higher in older age, females, ever-smokers, and hypertensive participants. The association of excess adiposity with the prevalence of hemorrhoidal disease differed by sex and parity.
| Item Type: | Article |
|---|---|
| Funders: | None |
| Uncontrolled Keywords: | Hemorrhoidal disease; Anorectal condition; Quality of life |
| Subjects: | Q Science > Q Science (General) T Technology > T Technology (General) |
| Divisions: | Faculty of Medicine |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 02 Aug 2022 06:29 |
| Last Modified: | 02 Aug 2022 06:29 |
| URI: | http://eprints.um.edu.my/id/eprint/33492 |
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