Thiang, Ee Lean and Chai, Choon Yip Stanley and Lee, Choon Weng and Takada, Hideshige and Wang, Ai Jun and Chai, Lay Ching and Bong, Chui Wei (2022) Tetracycline resistance and prevalence of tetracycline resistance genes in bacteria from marine aquaculture farms in Peninsular Malaysia. Sains Malaysiana, 51 (2). pp. 345-357. ISSN 0126-6039, DOI https://doi.org/10.17576/jsm-2022-5102-02.
Full text not available from this repository.Abstract
The indiscriminate use of antibiotic in aquaculture and leaching of antibiotic from aquaculture to the environment may led to the emergence and spread of antibiotic resistant bacteria and their resistant genes which is a public concern. Five tetracycline antibiotics (minocycline, doxycycline, chlorotetracycline, oxytetracycline and tetracycline) and 14 types of tetracycline genes, tet(A), (B), (C), (D), (E), (G), (K), (L), (M), (O), (S), (P), (Q) and (X)] were investigated in waters from,five marine aquaculture farms in Peninsular Malaysia. Tetracycline was detected in low concentrations from < LOQ to 25.6 ng/L. A total of 93 isolates of bacteria were isolated whereby Vibrio (n=29) and Pseudoalteromonas (n=7) were the predominant bacteria. Forty-eight of the isolates carried tet genes with 22.9% encoded multiple tet genes and 72.9% encoded a single tet gene. tet(A) (n = 20, 42%) was the most prevalent gene followed by tet(B) (n = 14, 29%) and tet(K) (n = 13, 27%). A few common tet carriers (Enterobacter, Vibrio, Photobacterium, and Pseudoalteromonas) carrying tet genes that have not been reported were identified. The values of the risk quotients (RQs) of tetracycline in Matang was 0.28 which posed a medium ecological risk to algae. Thus, the antibiotic residues in the aquaculture farm in Matang need to be monitored closely.
| Item Type: | Article |
|---|---|
| Funders: | Science and Technology Development Fund (STDF) Ministry of Higher Education & Scientific Research (MHESR) [Grant No: IOES-2014D & FP0482013A & SF022-2013], Universiti Malaya [Grant No: RU009D-2015 & PG309-2016A] |
| Uncontrolled Keywords: | Aquaculture; Risk assessment; Tetracycline; Tetracycline resistance gene |
| Subjects: | Q Science > Q Science (General) T Technology > T Technology (General) |
| Divisions: | Faculty of Science > Institute of Biological Sciences Deputy Vice Chancellor (Research & Innovation) Office > Institute of Ocean and Earth Sciences |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 02 Aug 2022 06:26 |
| Last Modified: | 02 Aug 2022 06:26 |
| URI: | http://eprints.um.edu.my/id/eprint/33444 |
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