Scar formation after skin injury to the human foetus in utero or the premature neonate

Morrison, W.A.; Hurley, J.V.; Ahmad, T.S.; Webster, H.R. Scar formation after skin injury to the human foetus in utero or the premature neonate. British Journal of Plastic Surgery, 52 (1). pp. 6-11.

[img]
Preview
PDF (Scar Formation) - Accepted Version [error in script]
Download (449Kb) | Preview

    Abstract

    A macroscopically visible scar was present at birth in three infants with a history of injury during amniocentesis at 16–20 weeks’ gestation. In several neonates born between 21 and 31 weeks’ gestation, chemical injury to the skin caused by extravasation of calcium gluconate healed by formation of a large scar. In the infant born at 21 weeks, biopsy of the injured area showed infiltration by large numbers of neutrophils and macrophages. It appears that a very immature neonate can mount a prominent inflammatory reaction and that both a midtrimester foetus and a very immature neonate heal injuries to the skin by scar formation and not by scarless healing.

    Item Type: Article
    Journal or Publication Title: British Journal of Plastic Surgery
    Uncontrolled Keywords: Scar; Human Foetal Scarring; Neonatal Scarring
    Subjects: R Medicine
    Divisions: Faculty of Medicine
    Depositing User: Nor Izzati Ab Razak
    Date Deposited: 11 Jan 2012 09:56
    Last Modified: 11 Jan 2012 09:56
    URI: http://eprints.um.edu.my/id/eprint/2484

    Actions (For repository staff only: Login required)

    View Item

    Document Downloads

    More statistics for this item...