Recent advances of aqueous two-phase flotation system for the recovery of biomolecules

Sankaran, Revathy and Parra Cruz, Ricardo Andres and Show, Pau Loke and Haw, Choon Yian and Lai, Sai Hin and Ng, Eng Poh and Ling, Tau Chuan (2019) Recent advances of aqueous two-phase flotation system for the recovery of biomolecules. Fluid Phase Equilibria, 501. p. 112271. ISSN 0378-3812

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Official URL: https://doi.org/10.1016/j.fluid.2019.112271

Abstract

Recently, aqueous two-phase flotation system (ATPF) has developed as an established technique for separation and purification technology. This process that utilizes the integration principle of aqueous two-phase system and solvent sublation has wide applications in the extraction and purification of biomaterials in biotechnology field. This method has advantages of high recovery yield, high purity, environmentally friendly technique and economical. Additionally, ATPF is easily scalable to large volume which presents an appealing substitute that meets the conditions of industry processes. In the last decade, several researches were conducted to develop this separation process. With the utilization of various integrated method, diverse application of ATPF for numerous product extraction has been explored. This paper discusses the basic principles of ATPF and review on the latest literature works in the advancement of various application and integration of ATPF in the extraction of biomolecules. Comprehensive study on the application of ATPF and the future directions of this new technology in the biotechnology field will be discussed. © 2019 Elsevier B.V.

Item Type: Article
Uncontrolled Keywords: Aqueous two phase flotation; Aqueous two phase system; Solvent sublation; Purification; Separation
Subjects: Q Science > Q Science (General)
Q Science > QR Microbiology
T Technology > TA Engineering (General). Civil engineering (General)
T Technology > TP Chemical technology
Divisions: Faculty of Engineering
Faculty of Science > Institute of Biological Sciences
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 22 Jan 2020 02:58
Last Modified: 22 Jan 2020 02:58
URI: http://eprints.um.edu.my/id/eprint/23530

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