Iron regulated outer membrane proteins (IROMPs) as potential targets against carbapenem-resistant Acinetobacter spp. isolated from a Medical Centre in Malaysia

Hwa, W.E.; Subramaniam, G.; Mansor, M.; Yan, O.S.; Anbazhagan, D.; Devi, S.S. (2010) Iron regulated outer membrane proteins (IROMPs) as potential targets against carbapenem-resistant Acinetobacter spp. isolated from a Medical Centre in Malaysia. The Indian journal of medical research, 131. pp. 578-83. ISSN 0971-5916

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Abstract

In this study, a 29-kDa OMP has been identified to be the major outer membrane protein in A. baumannii / calcoaceticus and loss of this porin and overexpression of IROMPs have contributed to carbapenem resistance. Polyclonal antibodies raised against IROMPs may have a role in antimicrobial therapy in these isolates.

Item Type: Article
Creators:
  1. Hwa, W.E.
  2. Subramaniam, G.
  3. Mansor, M.
  4. Yan, O.S.
  5. Anbazhagan, D.
  6. Devi, S.S.
Journal or Publication Title: The Indian journal of medical research
Additional Information: Department of Medical Microbiology, Faculty of Medicine, University Malaya Kuala Lumpur, Malaysia.
Uncontrolled Keywords: Acinetobacter baumannii/drug effects
Subjects: R Medicine
Divisions: Faculty of Medicine
Depositing User: Mr. Faizal Hamzah
Date Deposited: 17 May 2011 10:04
Last Modified: 11 Dec 2014 15:53
URI: http://eprints.um.edu.my/id/eprint/1231

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