Macrorestriction analysis of streptococcus agalactiae (group B Streptococcus) isolated from Malaysia

Thong, Kwai Lin and Goh, Yee Ling and Leong, Wing Kong and Lim, Chin Theam and Ngeow, Yun Fong (2004) Macrorestriction analysis of streptococcus agalactiae (group B Streptococcus) isolated from Malaysia. Journal of Medical Microbiology, 53 (10). pp. 991-997. ISSN 0022-2615, DOI

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Streptococcus agalactiae or group B streptococci (GBS) often colonize the gastrointestinal and urogenital tracts of women, who may transmit these organisms to their offspring during the birth process. Using PFGE analysis, the genetic diversity of GBS was studied for strains isolated from pregnant women and their newborn infants in a teaching hospital. A total of 48 different PFGE profiles were obtained from 123 strains, with one profile (S1) appearing to be predominant among both groups studied, There was good overall correlation between the profiles obtained for strains from mother-infant pairs and for strains isolated from different body sites in the same individual. Occasional discrepancies seen in related body sites and among mother-infant pairs suggest concurrent carriage of different strains in the same individual as well as the possibility of an environmental source of organism for the neonate. The overall results demonstrated that many variants of GBS strains occur in Malaysia.

Item Type: Article
Additional Information: Institute of Biological Sciences, Faculty of Science Building, University of Malaya, 50603 Kuala Lumpur, MALAYSIA
Uncontrolled Keywords: GBS, group B streptococci; PFP, PFGE profile
Subjects: Q Science > Q Science (General)
Q Science > QR Microbiology
Divisions: Faculty of Science > Institute of Biological Sciences
Faculty of Medicine
Depositing User: miss munirah saadom
Date Deposited: 16 Apr 2013 01:38
Last Modified: 15 Oct 2018 02:22

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