Pharmaceuticals, hormones, plasticizers, and pesticides in drinking water

Wee, Sze Yee and Ismail, Nur Afifah Hanun and Mohamad Haron, Didi Erwandi and Yusoff, Fatimah Md. and Praveena, Sarva Mangala and Aris, Ahmad Zaharin (2022) Pharmaceuticals, hormones, plasticizers, and pesticides in drinking water. Journal of Hazardous Materials, 424 (A). ISSN 0304-3894, DOI

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Humans are exposed to endocrine disrupting compounds (EDCs) in tap water via drinking water. Currently, most of the analytical methods used to assess a long list of EDCs in drinking water have been made available only for a single group of EDCs and their metabolites, in contrast with other environmental matrices (e.g., surface water, sediments, and biota) for which more robust methods have been developed that allow detection of multiple groups. This study reveals an analytical method of one-step solid phase extraction, incorporated together with liquid chromatography-tandem mass spectrometry for the quantification of multiclass EDCs (i.e., pharmaceuticals, hormones, plasticizers, and pesticides) in drinking water. Fifteen multiclass EDCs significantly varied in amount between field samples (p < 0.05), with a maximum concentration of 17.63 ng/L observed. Daily exposure via drinking water is unlikely to pose a health risk (risk quotient < 1). This method serves as an analytical protocol for tracing multiclass EDC contamination in tap water as part of a multibarrier approach to ensure safe drinking water for good health and well-being. It represents a simpler one-step alternative tool for drinking water analysis, thereby avoiding the time-consuming and expensive multi-extraction steps that are generally needed for analyzing multiclass EDCs.

Item Type: Article
Funders: Ministry of Higher Education Malaysia under Trans-Disciplinary Research Grant Scheme [Grant No: TRGS/1/2016/UPM/02/6/1], Ministry of Science and Technology in South Korea through the International Environmental Research Institute of Gwangju Institute of Science and Technology [Grant No: IERI/2019]
Uncontrolled Keywords: Endocrine disrupting compound (EDC); Tap water; Water security; SPE-LC-MS; MS; Health risk assessment
Subjects: T Technology > TA Engineering (General). Civil engineering (General)
T Technology > TD Environmental technology. Sanitary engineering
Divisions: Faculty of Medicine
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 26 Apr 2022 04:03
Last Modified: 26 Apr 2022 04:03

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