Therapeutic potential of saffron, and its chemical components in the treatment of cancers and cardiovascular disorders: A review

Khan, A. and Muhamad, Nur Airina and Taha, R. M. and Mohamad, J. and Al-Shara, B. (2021) Therapeutic potential of saffron, and its chemical components in the treatment of cancers and cardiovascular disorders: A review. International Food Research Journal, 28 (5). pp. 871-892. ISSN 1985-4668,

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Abstract

Crocus sativus L., a medicinally important species of the Iridaceae family which produces the herb saffron, plays an effective role in combating various pathogenic disorders including cancers and cardiovascular diseases. Apart from its conventional colorant and aroma-inducing attributes, various phytochemical compounds associated with saffron are now being intensively studied. More than 300 phytochemical compounds, derived from saffron stigmas alone, belong to various classes of secondary metabolites such as carotenoids, terpenoids, flavonoids, and anthocyanins; and they have immense therapeutic applications. Furthermore, pharmacogenomic studies of saffron extracts have revealed promising biocompatible and anticancer potentials against various drug-resistant cell lines which reduce cellular division and proliferation of malignant cells. Keeping in view with the numerous pharmacological properties associated with saffron, the present review explicitly discusses the role of its elemental contents in the prevention and treatment of various cancers and cardiovascular ailments. (C) All Rights Reserved

Item Type: Article
Funders: University of Malaya Research Grant, UMRG (RP024A-14AFR), Postgraduate Research Grant, IPPP (PG063-2015B)
Uncontrolled Keywords: Cancer; Cardiovascular disease; Phytochemical; Saffron
Subjects: Q Science > Q Science (General)
Divisions: Faculty of Science > Institute of Biological Sciences
Depositing User: Ms Zaharah Ramly
Date Deposited: 25 Jul 2022 08:29
Last Modified: 25 Jul 2022 08:29
URI: http://eprints.um.edu.my/id/eprint/28123

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