Localised nodular pulmonary amyloidosis in a patient with sicca syndrome

Srinivas, Pangal and Liam, Chong Kin and Jayaram, Gita (2000) Localised nodular pulmonary amyloidosis in a patient with sicca syndrome. Medical Journal of Malaysia, 55 (3). pp. 385-387. ISSN 0300-5283,

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Official URL: http://www.e-mjm.org/2000/v55n3/Sicca_Syndrome.pdf


A 52 year old Chinese woman with a 25 year history of sicca syndrome (primary Sjogrens syndrome) was investigated for 3 episodes of haemoptysis. Clinical examination was unremarkable except for the presence of dry eyes and xerostomia. Computed tomography of the chest revealed a lobulated mass in the posterior basal segment of the left lower lobe. Histopathological examination of this resected nodule confirmed the diagnosis of nodular amyloidosis. The normal radiolabelled serum amyloid P component scintigraphy and the absence of monoclonal plasma cell dyscrasia in the bone marrow strongly support the diagnosis of localised nodular pulmonary AL amyloidosis in this patient. Nodular pulmonary amyloidosis can be associated with sicca syndrome and often simulates bronchogenic carcinoma, bronchiectasis or pulmonary tuberculosis.

Item Type: Article
Uncontrolled Keywords: Amyloidosis; Female; Humans; Lung Diseases; Middle Aged; Sjogren's Syndrome; Tomography, X-Ray Computed
Subjects: R Medicine
Divisions: Faculty of Medicine
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 12 Apr 2021 03:24
Last Modified: 12 Apr 2021 03:24
URI: http://eprints.um.edu.my/id/eprint/25869

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