Ulcerative colitis in Malaysians

Pailoor, Jayalakshmi and Wong, N.W. and Malik, A.K. and Goh, K.L. (1996) Ulcerative colitis in Malaysians. Journal of the University of Malaya Medical Centre (JUMMEC), 1 (2). pp. 39-42. ISSN 1823-7339,

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Official URL: https://jummec.um.edu.my/article/view/4391


A review of all colonic biopsies received by the Department of Pathol­ ogy duringa 8-year period revealed 41cases of ulcerative colitis (UC). The diagnosis was based on histological and clinical features. The age range of patients was be­ tween 14 - 76 years with a median age of 35.4 years. The disease was more prevalent among Indians. The common presenting symptoms were diarrhoea (100%) and haematochezia (83%). The extent of colonic involvement varied. Twelve patients ( 29.2%) had pancolitis and 8 (19.5 %) had proctitis. Extraintestinal manifestations were rare and only one patient had pyoderma gangrenosum. One patient developed multifocal colorectal cancer10 years after the inial diagnosis of UC and died 2 years later due to metastases. Histology plays an important role in the diagnosis and man­ agementof patients with UC.Wenoted a goodcorrelation between clinical and patho­ logical features. The most recent colonic biopsy showed features of chronic UC with activity in 34 cases and features of remission in 4 cases.

Item Type: Article
Additional Information: KK
Uncontrolled Keywords: Ulcerative colitis; Malaysians; pathology
Subjects: R Medicine
Divisions: Faculty of Medicine
Depositing User: Mr Jasny Razali
Date Deposited: 02 Jun 2020 03:05
Last Modified: 02 Jun 2020 03:05
URI: http://eprints.um.edu.my/id/eprint/24439

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