Collaborative intervention between pharmacists and physicians on elderly patients: a randomized controlled trial

Shim, Yee Wei and Chua, Siew Siang and Wong, Hui Chin and Alwi, Syireen (2018) Collaborative intervention between pharmacists and physicians on elderly patients: a randomized controlled trial. Therapeutics and Clinical Risk Management, 14. pp. 1115-1125. ISSN 1176-6336, DOI

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Background: The elderly population is the largest consumer of medications as this age group is at high risk for developing chronic diseases. However, medication use among elderly people is complicated by an increased risk of drug-related problems. Therefore, the present study was conducted to investigate the effects of collaborative interventions between pharmacists and physicians on health-related outcomes of elderly patients. Patients and methods: This was a randomized controlled trial (RCT) conducted on elderly outpatients who sought treatment in the Medical Outpatient Department of a public tertiary hospital in Malaysia and who were taking at least five medications. The participants were randomly allocated to the intervention and control groups. The intervention group received pharmaceutical care from a pharmacist in collaboration with physicians and was followed-up for 6 months, while the control group received usual care in the outpatient pharmacy. Results: A total of 73 participants in the intervention group and 79 participants in the control group completed the study. Participants in the intervention group had significantly better medication adherence (median =7.0 vs 5.0, U=1224.5, p<0.001, r=0.503) and better Medication Appropriateness Index (MAI) score (median =8.0 vs 20.0, U=749.5, p<0.001, r=0.639). Conclusion: Collaborative interventions between pharmacists and physicians improved medication adherence and MAI scores of the elderly patients. Therefore, such services should be implemented in all hospitals, especially in countries where pharmacists are still not playing a substantial role in patient care. Trial registration: NMRR-12-958-13020.

Item Type: Article
Funders: University of Malaya: research grant (PG017-2013A)
Uncontrolled Keywords: geriatric; medication adherence; Medication Appropriate Index; MAI; intervention
Subjects: R Medicine
Divisions: Faculty of Medicine
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 13 Mar 2019 02:01
Last Modified: 13 Mar 2019 02:01

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