Choroidal thickness in Malaysian eyes with full-thickness macular holes

Tan, Chew Y. and Vengadasalam, Selva Raja and Samsudin, Amir and Khaliddin, Nurliza (2018) Choroidal thickness in Malaysian eyes with full-thickness macular holes. International Eye Science, 18 (3). pp. 401-405. ISSN 1672-5123, DOI

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AIM: To compare choroidal thickness at the macula in eyes with unilateral idiopathic full-thickness macular holes (FTMH) with that of unaffected fellow eyes, and eyes of normal control patients. METHODS: Cross-sectional study. Thirty patients with unilateral idiopathic FTMH and thirty age, sex, and race-matched controls were recruited. Axial lengths were measured using laser interferometry. Enhanced depth imaging optical coherence tomography images were obtained using Heidelberg spectral-domain optical coherence tomography. Choroidal thickness was measured at the fovea, and at 1 mm and 2 mm nasally, temporally, superiorly and inferiorly from the center of the fovea. Statistical analysis was performed using independent and paired t-tests, chi-square tests, and Pearson correlation tests (P<0.05). RESULTS: The mean subfoveal choroidal thickness was 201.0±44.0 μm in the FTMH group, 225.3±51.4 μm in the fellow eye group and 262.3±70.3 μm in the control group. The choroid was thinner in FTMH eyes at all locations when compared to control eyes (P<0.05). The fellow eye group also had thinner choroids than the control group at all locations except at 1 mm and 2 mm nasal to the fovea (P<0.05). Choroidal thickness in the FTMH group was lower than in the fellow eye group, but the differences were not statistically significant (P>0.05). Choroidal thickness was generally highest subfoveally and lowest nasally. Subfoveal choroidal thickness was negatively correlated with age (r=-0.278, P=0.032), and axial length (r=-0.328, P=0.011). CONCLUSION: Choroidal thickness is lower in both eyes of patients with unilateral FTMH compared to healthy control eyes.

Item Type: Article
Uncontrolled Keywords: choroidal thickness; macular holes; optical coherence tomography; spectral-domain; enhanced depth imaging; Heidelberg
Subjects: R Medicine
Divisions: Faculty of Medicine
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 04 Mar 2019 01:56
Last Modified: 04 Mar 2019 01:56

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