tert-Butyl 2-{[2,8-bis(trifluoromethyl)-quinolin-4-yl](hydroxy)methyl}-piperidi ne-1-carboxylate

Goncalves, R.S.B. and de Souza, M.V.N. and Wardell, J.L. and Wardell, S.M.S.V. and Tiekink, E.R.T. (2011) tert-Butyl 2-{[2,8-bis(trifluoromethyl)-quinolin-4-yl](hydroxy)methyl}-piperidi ne-1-carboxylate. Acta Crystallographica Section E: Structure Reports Online, 67 (12). O3315-U163. ISSN 1600-5368,

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The title molecule, C22H24F6N2O3, adopts a folded conformation whereby the carboxylate residue lies over the quinolinyl residue, with the dihedral angle between the carbamate and quinoline planes being 41.64 (7)degrees. Helical supramolecular C(7) chains sustained by O-H center dot center dot center dot O hydrogen bonds propagating along the a-axis direction feature in the crystal packing. The F atoms of one of the CF3 groups are disordered over two orientations; the major component has a site occupancy of 0.824 (7).

Item Type: Article
Subjects: Q Science > QC Physics
Depositing User: MR Faizal II H
Date Deposited: 07 Nov 2015 02:44
Last Modified: 31 Jan 2019 04:11
URI: http://eprints.um.edu.my/id/eprint/14632

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