Symptomatic anaemia 17 years after double valve replacement

Wong, M.H. and Chee, K.H. and Azman, W. (2009) Symptomatic anaemia 17 years after double valve replacement. Singapore Medical Journal, 50 (10). pp. 362-4. ISSN 0037-5675, DOI 19907876.

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A 40-year-old Malay woman presented with increasing lethargy, palpitation and shortness of breath, 17 years after a mitral and aortic valve replacement. A Starr-Edwards prosthetic valve replaced the mitral valve, and a Bjork-Shiley prosthetic valve replaced the aortic valve. Biochemical parameters demonstrated intravascular haemolysis, as evidenced by haemoglobin 7.8 g/dL, reticulocyte count 8.4%, lactate dehydrogenase 2,057 IU/L and low haptoglobulin levels (less than 6 mg/dL). Transoesophageal echocardiography revealed a paravalvular leakage over the mitral valve. The haemoglobin levels remained persistently low despite frequent blood transfusions. She successfully underwent a second mitral valve replacement. Her anaemia resolved subsequently.

Item Type: Article
Additional Information: Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, Malaysia.
Uncontrolled Keywords: Adult; Anemia/diagnosis; Anemia/etiology
Subjects: R Medicine
Divisions: Faculty of Medicine
Depositing User: Mr. Faizal Hamzah
Date Deposited: 05 May 2011 01:46
Last Modified: 14 Jan 2019 01:37

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