Smart combination of β-cyclodextrin polymer-conjugated magnetic nanosorbent for potential adsorption of deoxyribonucleic acid

Goh, Ying Hwa and Boon, Yih Hui and Jairaj Moses, Emmanuel and Shahriman, Mohamad Shariff and Md Yusoff, Masrudin and Yahaya, Noorfatimah and Sambasevam, Kavirajaa Pandian and Surikumaran, Hemavathy and Chandrasekaram, Kumuthini and Raoov, Muggundha (2019) Smart combination of β-cyclodextrin polymer-conjugated magnetic nanosorbent for potential adsorption of deoxyribonucleic acid. Separation Science and Technology, 54 (6). pp. 902-915. ISSN 0149-6395, DOI https://doi.org/10.1080/01496395.2018.1524485.

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Official URL: https://doi.org/10.1080/01496395.2018.1524485

Abstract

We reported the synthesis and characterization of Fe 3 O 4 magnetic nanoparticles modified β-cyclodextrin polymer (MNP@βCD-TDI) for the adsorption of deoxyribonucleic acid (DNA). The synthesized MNP@βCD-TDI was characterized by Fourier Transform Infra-Red spectroscopy and Vibrating Sample Magnetometer. Experiments were performed in a batch mode and parameters that affected the DNA adsorption were investigated. An evaluation of the adsorption behavior revealed that Freundlich model and pseudo-second-order fit the equilibrium data. The adsorption efficiency of DNA was found to be at 70 ± 5 % after being recycled three times. This study could be used as a general platform for future work on DNA adsorption and enrichment.

Item Type: Article
Funders: Research University Grant, Universiti Sains Malaysia [RUI: 1001/ CIPPT/811322], Fundamental Research Grant Scheme, Ministry of Higher Education (MOHE), Malaysia [FRGS: 203/CIPPT/6711557]
Uncontrolled Keywords: β-Cyclodextrin; adsorption; magnetic nanoparticles; biomedical application; inclusion complex
Subjects: Q Science > Q Science (General)
Q Science > QD Chemistry
Divisions: Faculty of Science > Department of Chemistry
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 04 Nov 2019 09:22
Last Modified: 04 Nov 2019 09:22
URI: http://eprints.um.edu.my/id/eprint/22965

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