The Fabrication and Characterization of PCL/Rice husk derived bioactive glass-ceramic composite scaffolds

Naghizadeh, F. and Sultana, N. and Kadir, M.R.A. and Shihabudin, T.M.T.M. and Hussain, R. and Kamarul, Tunku (2014) The Fabrication and Characterization of PCL/Rice husk derived bioactive glass-ceramic composite scaffolds. Journal of Nanomaterials (JNM), 2014 (2014). ISSN 1687-4110, DOI https://doi.org/10.1155/2014/253185.

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Abstract

The present study was conducted to fabricate a 3D scaffold using polycaprolactone (PCL) and silicate based bioactive glass-ceramic (R-SBgC). Different concentrations of R-SBgC prepared from rice husk ash (RHA) were combined with PCL to fabricate a composite scaffold using thermally induced phase separation (TIPS) method. The products were then characterized using SEM and EDX. The results demonstrated that R-SBgC in PCL matrix produced a bioactive material which has highly porous structure with interconnected porosities. There appears to be a relationship between the increase in R-SBgC concentration and increased material density and compressive modulus; however, increasing R-SBgC concentration result in reduced scaffold porosity. In conclusion, it is possible to fabricate a PCL/bioactive glass-ceramic composite from processed rice husk. Varying the R-SBgC concentrations can control the properties of this material, which is useful in the development of the ideal scaffold intended for use as a bone substitute in nonload bearing sites.

Item Type:	Article
Funders:	UNSPECIFIED
Additional Information:	ISI Document Delivery No.: 303HK Times Cited: 0 Cited Reference Count: 29 Naghizadeh, Farnaz Sultana, Naznin Kadir, Mohammed Rafiq Abdul Shihabudin, Tengku Muzaffar Tengku Md Hussain, Rafaqat Kamarul, Tunku Universiti Teknologi Malaysia (UTM); Research Management Center (RMC); Ministry of Higher Education (MOHE); Faculty of Bioscience and Medical Engineering (FBME); UTM research Grants 79412, 4F126, 03H13; University of Malaya HIR-MOHE research grant initiative The authors acknowledge the Universiti Teknologi Malaysia (UTM), the Research Management Center (RMC), the Ministry of Higher Education (MOHE), and the Faculty of Bioscience and Medical Engineering (FBME). This research was supported by UTM research Grants (vote: 79412 and 4F126, 03H13). One of the authors of this paper is supported by the University of Malaya HIR-MOHE research grant initiative. Hindawi publishing corporation New york
Uncontrolled Keywords:	in-vitro characterization; mechanical-properties; calcium phosphates; graft substitutes; bone-graft; rice husk; ; silica; biomaterials; regeneration
Subjects:	R Medicine
Divisions:	Faculty of Medicine
Depositing User:	Ms Haslinda Lahuddin
Date Deposited:	29 Apr 2014 01:39
Last Modified:	10 Oct 2018 08:59
URI:	http://eprints.um.edu.my/id/eprint/9860

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• The Fabrication and Characterization of PCL/Rice husk derived bioactive glass-ceramic composite scaffolds. (deposited 29 Apr 2014 01:39) [Currently Displayed]

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