Establishing referance intervals for haematological parameters, soluble serum transferrin receptor and serum transferrin in a tertiary hospital in Malaysia

Hemalatha, S. and Thatcheiany, K. and Pavai, S. (2014) Establishing referance intervals for haematological parameters, soluble serum transferrin receptor and serum transferrin in a tertiary hospital in Malaysia. In: Pathology Update 2014, 21 - 23 February 2014, Melbourne Convention Centre, South Wharf, Melbourne.

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Abstract

Clinical laboratory testing is an integral part of diagnosis, treatment and prognosis that ensures quality and effective healthcare. Factors like genetics, dietary intake, gender, age, level of physical activity, altitude above sea level etc. can alter biochemical and haematological parameters in a population Variation can also occur based on the instrument or methodology being used. Thus it is pivotal for laboratories to establish their own reference intervals specific for their population. In our laboratory we have been interpreting CBC results based on the reference value established for the western population. In the context above, we decided to establish our own reference value by studying healthy Malaysian adults. Iron deficiency is also a common clinical problem in our population. Its distinction from anaemia secondary to infection, inflammation or malignancy remains a clinical challenge. The conventional laboratory tests of iron status are influenced by several factors but additional markers such as serum transferrin and serum soluble transferrin receptor helps in better evaluation of iron status. The aim of this study was to determine reference interval for haematology parameters and serum iron markers that includes serum soluble transferrin receptor and serum transferrin.

Item Type: Conference or Workshop Item (Lecture)
Additional Information: Shanmugam Hemalatha, Kumariah Thatcheiany and Sthaneshwar Pavai Department of Pathology, Faculty of Medicine, University Malaya, Kuala Lumpur, Malaysia
Uncontrolled Keywords: Haematological parameters; Serum transferrin receptor; serum transferrin; Pathology
Subjects: R Medicine
R Medicine > RB Pathology
Divisions: Faculty of Medicine
Depositing User: Miss Ilina Syazwani Musa
Date Deposited: 10 Apr 2014 03:57
Last Modified: 29 Oct 2014 00:34
URI: http://eprints.um.edu.my/id/eprint/9835

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