Modeling of hemoglobin in dengue fever and dengue hemorrhagic fever using bioelectrical impedance

Ibrahim, F. and Ismail, N.A. and Taib, M.N. and Wan Abas, W.A.B. (2004) Modeling of hemoglobin in dengue fever and dengue hemorrhagic fever using bioelectrical impedance. Physiological Measurement, 25 (3). pp. 607-615. ISSN 1361-6579

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This paper describes a model for predicting hemoglobin (Hb) by using bioelectrical impedance analysis (BIA) in dengue patients in the Hospital Universiti Kebangsaan Malaysia (HUKM). Bioelectrical impedance measurements were conducted on 83 (47 males and 36 females) serologically confirmed dengue fever (DF) and dengue hemorrhagic fever (DHF) patients during their hospitalization. The predictive equation for Hb was derived using multivariate analysis. We investigated all the parameters in BIA, patients' symptom and demographic data. In this developed model, four predictors (reactance (Xc), sex, weight and vomiting) were found to be the best predictive factors for modeling Hb in dengue patients. However, the model can only explain approximately 42 of the variation in Hb status, thus single frequency bio-impedance stand-alone technique is insufficient to monitor Hb for the DF and DHF patients. Further investigation using multi-frequency BIA is recommended in modeling Hb to achieve the most parsimonious model.

Item Type: Article
Additional Information: Cited By (since 1996):13 Export Date: 29 January 2014 Source: Scopus CODEN: PMEAE PubMed ID: 15253113 Language of Original Document: English Correspondence Address: Ibrahim, F.; Department of Biomedical Engineering, Faculty of Engineering, University of Malaya, 50603, Kuala Lumpur, Malaysia Chemicals/CAS: hemoglobin, 9008-02-0; Hemoglobins References: Berhman, R.E., Kliegman, R.M., (2002) Nelson Essentials of Paediatrics 4th Edn., p. 610. , Philadelphia, PA: Saunders; Bethell, D.B., Noninvasive measurement of microvascular leakage in patients with dengue hemorrhagic fever (2001) Clin. 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Uncontrolled Keywords: Bioelectrical impedance, Dengue hemorrhagic fever, Hemoglobin, Modeling, Multivariate analysis, adolescent, adult, analytic method, article, bioelectrical impedance analysis, bioenergy, blood sampling, blood vessel permeability, body weight, calculation, demography, dengue, evaluation, extracellular space, female, hemoglobin determination, human, impedance, intracellular space, major clinical study, Malaysia, male, mathematical model, measurement, osmotic pressure, parameter, patient monitoring, prediction, priority journal, school child, serodiagnosis, sex difference, symptom, technique, vomiting, Child, Diagnosis, Computer-Assisted, Hemoglobins, Humans, Middle Aged, Models, Biological, Models, Statistical, Plethysmography, Impedance, Reproducibility of Results, Sensitivity and Specificity, Statistics, Bia
Subjects: T Technology > T Technology (General)
T Technology > TA Engineering (General). Civil engineering (General)
Divisions: Faculty of Engineering
Depositing User: Mr Jenal S
Date Deposited: 07 Apr 2014 02:49
Last Modified: 09 Aug 2018 08:32

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