An oral cancer biobank initiative: a platform for multidisciplinary research in a developing country

Zain, R.B. and Athirajan, V. and Ghani, W.M.N. and Razak, I.A. and Latifah, R.J.R. and Ismail, S.M. and Sallam, A.A. and Bustam, A.Z. and Rahman, Z.A.A. and Hussien, A. and Talib, N. and Cheong, S.C. and Jallaludin, A. (2013) An oral cancer biobank initiative: a platform for multidisciplinary research in a developing country. Cell and Tissue Banking, 14 (1). pp. 45-52.

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Abstract

Identification of diagnostic markers for early detection and development of novel and therapeutic agents for effective patient management are the main motivation for cancer research. Biological specimens from large cohort and case-control studies which are crucial in providing successful research outcomes are often the limiting factor that hinders research efforts, especially in developing countries. Therefore, the Malaysian Oral Cancer Database and Tissue Bank System (MOCDTBS) were established to systematically collect large number of samples with comprehensive sociodemographic, clinicopathological, management strategies, quality of life and associated patient follow-up data to facilitate oral cancer research in Malaysia. The MOCDTBS also promotes sharing among researchers and the development of a multidisciplinary research team. The following article aims to describe the process of setting-up and managing the MOCDTBS.

Item Type: Article
Additional Information: ISI Document Delivery No.: 150XM Times Cited: 0 Cited Reference Count: 25 Cited References: American Cancer Society, 1997, CA CANC J CLIN, V47, P5 Cheong SC, 2009, ORAL ONCOL, V45, P712, DOI 10.1016/j.oraloncology.2008.11.002 Dom RM, 2008, AUST ASIAN J CANC, V7, P209 Doss JG, 2011, ORAL ONCOL, V47, P648, DOI 10.1016/j.oraloncology.2011.04.023 Hamid S, 2007, INT J MOL MED, V19, P453 Hamid S, 2009, ORAL ONCOL, V45, P496, DOI 10.1016/j.oraloncology.2008.06.003 Hansson MG, 2006, LANCET ONCOL, V7, P266, DOI 10.1016/S1470-2045(06)70618-0 Hansson MG, 2005, EUR J PUBLIC HEALTH, V16, P433 Hewitt R, 2010, BIOPRESERV BIOBANK, V7, P143, DOI DOI 10.1089/BIO.2010.0003 Lee CH, 2011, INT J CANCER, V129, P1741, DOI 10.1002/ijc.25809 Liao CT, 2010, ANN SURG ONCOL, V17, P2984, DOI 10.1245/s10434-010-1174-1 Merz JF, 1997, J INVEST MED, V45, P252 Molnar MJ, 2006, CELL IMMUNOL, V244, P101, DOI 10.1016/j.cellimm.2007.02.013 Saini R, 2011, J CANCER RES CLIN, V137, P311, DOI 10.1007/s00432-010-0886-8 Saleh A, 2010, ORAL ONCOL, V46, P379, DOI 10.1016/j.oraloncology.2010.02.022 Schwartz JL, 2000, ORAL ONCOL, V36, P225, DOI 10.1016/S1368-8375(99)00077-9 Simon J, 2007, EUR J HUM GENET, V15, P528, DOI 10.1038/sj.ejhg.5201810 Wan Mustafa WM, 2011, HEAD NECK-J SCI SPEC, V34, P344 Warnakulasuriya S, 2009, ORAL ONCOL, V45, P309, DOI 10.1016/j.oraloncology.2008.06.002 Watson RWG, 2010, NAT REV CANCER, V10, P646, DOI 10.1038/nrc2913 Zain RB, 2005, J EXP CLIN CANC RES, V24, P207 Ghani WMN, 2011, BMC PUBLIC HEALTH, V11, DOI 10.1186/1471-2458-11-82 Zain RB, 2011, ASIAN PAC J CANCER P, V12, P1 Zain RB, 2009, ASIAN PAC J CANCER P, V10, P513 Yuille M, 2008, BRIEF BIOINFORM, V9, P14, DOI 10.1093/bib/bbm050 Zain, Rosnah Binti Athirajan, Vimmitra Ghani, Wan Maria Nabillah Razak, Ishak Abdul Latifah, Raja Jalaludin Raja Ismail, Siti Mazlipah Sallam, Atiya Abdul Bustam, Anita Zarina Rahman, Zainal Ariff Abdul Hussien, Adam Talib, Norain Cheong, Sok Ching Jallaludin, Amin Ministry of Science, Technology and Innovation (MOSTI) Malaysia: Intensified Research in Priority Areas (IRPA) of the 8th Malaysia Plan (RMK8) Fund 06-02-03-0174 PR 0054/05-05, 06-00-00-0000; E-Science Fund 06-01-03-SF0089 The development of the biobank was supported by grants from the Ministry of Science, Technology and Innovation (MOSTI) Malaysia: Intensified Research in Priority Areas (IRPA) of the 8th Malaysia Plan (RMK8) Fund project number: 06-02-03-0174 PR 0054/05-05; 06-00-00-0000 and E-Science Fund project number: 06-01-03-SF0089. The continuation and maintenance of the biobank are currently supported by the University of Malaya through an operative and human resource budget to the Oral Cancer Research and Coordinating Centre (OCRCC), Faculty of Dentistry. The authors would like to thank Dr. Wan Mahadzir Wan Mustafa, Dr. Thomas Abraham, Dr. Norma Jalil, Dr. Yuen Kar Mun, Dr. Tay Keng Kiong, all research coordinators and staffs from Oral Health Division, Ministry of Health Malaysia at various participating hospitals for their invaluable effort in data and specimen collection. Our deepest gratitude is also dedicated to all members of this project for their support and endless effort in developing and maintaining the biobank. Springer Dordrecht
Uncontrolled Keywords: Oral cancer Biobank Malaysia Multidisciplinary team buccal mucosa carcinoma tongue asia
Subjects: R Medicine > RK Dentistry
Divisions: Faculty of Dentistry > Dept of General Dental Practice And Oral & Maxillofacial Imaging
Depositing User: Mr Ahmad Azwan Azman
Date Deposited: 17 Jul 2013 00:20
Last Modified: 17 Jul 2013 00:20
URI: http://eprints.um.edu.my/id/eprint/8123

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