Ariffin, Azhar and Khan, M.N. and Abdullah, N. and Sim, Y.L. (2007) Effects Of Mixed Aqueous-Organic Cosolvents On The Rates Of Cleavage Of N-(2'-Hydroxyphenyl)Phthalimide (1) And N-(2'-Methoxyphenyl)-Phthalimide (2) In Alkaline Media. Progress in Reaction Kinetics and Mechanism, 32 (2). pp. 51-71. ISSN 1468-6783, DOI https://doi.org/10.3184/146867806x211541.
Full text not available from this repository.Abstract
The effects of mixed H2O-OCS (where organic cosolvents (OCS) = methanol, ethanol, 1-propanol, 2-propanol, 1,4-dioxan and acetonitrile) on the first-order rate constants, k(obs), for hydrolysis of I at 1.0 X 10(-3) M NaOH and 2 at 2.0 x 10(-3) M NaOH show a nonlinear decrease in k(obs), with increasing contents of OCS. The k(obs), - decreasing sensitivity of mixed H2O - OCS solvents within 5 X% v/v OCS, where X ranges from 50 to 90, is ca 2- to 9-fold larger for hydrolysis of 2 than that of 1. This observed characteristic difference is attributed to the occurrence of different rate laws in these reactions, i.e. rate = k(w) [1(-)][H2O] and rate = k(OH) [2][HO-] in the hydrolyses of 1 and 2, respectively.
| Item Type: | Article |
|---|---|
| Funders: | UNSPECIFIED |
| Additional Information: | Department of Chemistry, Faculty of Science Building, University of Malaya, 50603 Kuala Lumpur, MALAYSIA |
| Uncontrolled Keywords: | mixed h2o-ocs, methanol, ethanol, 1-propanol, 2-propanol, 1,4-dioxan, acetonitrile, first-order rate constants, hydrolysis, ionized phenyl salicylate, structure-reactivity correlations, base-catalyzed cleavage secondary-amines, acyl transfer, hydrolysis, kinetics, mechanism, solvents, esters |
| Subjects: | Q Science > QD Chemistry |
| Divisions: | Faculty of Science > Department of Chemistry |
| Depositing User: | Miss Malisa Diana |
| Date Deposited: | 03 Jul 2013 09:03 |
| Last Modified: | 27 Aug 2019 06:11 |
| URI: | http://eprints.um.edu.my/id/eprint/8048 |
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