Ariffin, Azhar and Khan, M.N. (2005) Unexpected rate retardation in the formation of phthalic anhydride from N-Methylphthalamic Acid in acidic H2O-CH3CN medium. Bulletin of the Korean Chemical Society, 26 (7). pp. 1037-1043. ISSN 0253-2964,
Full text not available from this repository.Abstract
Kinetic study on the cleavage of N-methylphthalamic acid (NMPA) in mixed acidic aqueous-acetonitrile solvent reveals the formation of both phthalic anhydride (PAn) (through O-cyclization) and N-methylphthalimide (NMPT) (through N-cyclization). The formation of NMPT varies from similar to 20% to similar to 3% with the increase in the content of acetonitrile from 2 to 70% v/v. Pseudo first-order rate constants for the formation of PAn are more than 4-fold larger than those for the formation of NMPT at 2% v/v CH3CN in mixed aqueous solvents. Pseudo first-order rate constants for alkaline hydrolysis of NMPT reveal a nonlinear decrease with increase in the content of CH3CN in mixed aqueous solvents.
| Item Type: | Article |
|---|---|
| Funders: | UNSPECIFIED |
| Additional Information: | Department of Chemistry, Faculty of Science Building, University of Malaya, 50603 Kuala Lumpur, MALAYSIA |
| Uncontrolled Keywords: | phthalic anhydride, kinetics, hydrolysis, o-cyclization and n-cyclization of n-methylphthalamic acid, intramolecular catalysis, amide hydrolysis, alkaline-hydrolysis, aqueous cleavage, imide formation, mechanism, kinetics, cyclization, hydroxyphthalimide, participation |
| Subjects: | Q Science > QD Chemistry |
| Divisions: | Faculty of Science > Department of Chemistry |
| Depositing User: | Miss Malisa Diana |
| Date Deposited: | 03 Jul 2013 09:06 |
| Last Modified: | 27 Aug 2019 06:05 |
| URI: | http://eprints.um.edu.my/id/eprint/8044 |
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