Breast cancer in a multi-ethnic Asian setting: results from the Singapore-Malaysia hospital-based breast cancer registry

Pathy, N.B.; Yip, C.H.; Taib, N.A.; Hartman, M.; Saxena, N.; Iau, P.; Bulgiba, A.M.; Lee, S.C.; Lim, S.E.; Wong, J.E.L.; Verkooijen, H.M. (2011) Breast cancer in a multi-ethnic Asian setting: results from the Singapore-Malaysia hospital-based breast cancer registry. The Breast, 20 (2). s75-s80. ISSN 09609776

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Abstract

Two hospital-based breast cancer databases (University Malaya Medical Center, Malaysia [n = 1513] and National University Hospital, Singapore [n = 2545]) were merged into a regional registry of breast cancer patients diagnosed between 1990 and 2007. A review of the data found 51% of patients diagnosed before the age of 50 years. and 72% percent of the women were Chinese followed by Malays (16%), Indians (8%), and other races (4%). Median tumor size at presentation was 26 mm and about 25% of patients presented with TNM stage III or IV disease. Most tumors were of ductal histology (87%). Fifty-seven percent of tumors were estrogen receptor positive and 40% were poorly differentiated. Of those patients who had surgery, 70% had mastectomy while 30% had breast conserving surgery. Overall, chemotherapy was administered to 56% of patients and hormonal treatment to 60%. Five-year overall survival was 82.5% in patients with TNM stage 0 to stage II cancer, and 30.2% in those with later stages.

Item Type: Article
Creators:
  1. Pathy, N.B.
  2. Yip, C.H.
  3. Taib, N.A.
  4. Hartman, M.
  5. Saxena, N.
  6. Iau, P.
  7. Bulgiba, A.M.
  8. Lee, S.C.
  9. Lim, S.E.
  10. Wong, J.E.L.
  11. Verkooijen, H.M.
Journal or Publication Title: The Breast
Uncontrolled Keywords: Breast cancer; Asian; Asia; Cancer registry;
Subjects: R Medicine
Divisions: Faculty of Medicine
Depositing User: Zanaria Saupi Udin
Date Deposited: 19 Apr 2011 13:12
Last Modified: 11 Dec 2014 16:47
URI: http://eprints.um.edu.my/id/eprint/789

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