Khosravi, Yalda and Tay, Sun Tee and Vadivelu, Jamuna (2010) Metallo-β-lactamase–producing imipenem-resistant Pseudomonas aeruginosa clinical isolates in a university teaching hospital in Malaysia: detection of IMP-7 and first identification of IMP-4, VIM-2, and VIM-11. Diagnostic Microbiology and Infectious Disease, 67 (3). pp. 294-296. ISSN 0732-8893, DOI https://doi.org/10.1016/j.diagmicrobio.2010.02.010.
Full text not available from this repository.Abstract
Ninety (n = 90) imipenem-resistant Pseudomonas aeruginosa (IRPA) clinical isolates collected randomly during 2005 to 2008 from University Malaya Medical Center were assessed for the presence of different variants of metallo-β-lactamase (MBL) genes. Polymerase chain reaction (PCR) assay detected 32 (n = 32) MBL gene PCR-positive isolates with the presence of blaIMP gene in 14 (n = 14) and blaVIM in 18 (n = 18) isolates. Four allelic variants, blaIMP-7 (12 isolates), blaIMP-4 (2 isolates), blaVIM-2 (17 isolates), and blaVIM-11 (1 isolate), of MBL genes were identified. This study is the first report of detection of blaIMP-4, blaVIM-2, and blaVIM-11 MBL genes from IRPA clinical isolates in Malaysia.
| Item Type: | Article |
|---|---|
| Funders: | UNSPECIFIED |
| Uncontrolled Keywords: | Metallo-β-lactamase (MBL) genes; Pseudomonas aeruginosa; Imipenem resistance; blaIMP; blaVIM; Carbapenems |
| Subjects: | R Medicine |
| Divisions: | Faculty of Medicine |
| Depositing User: | Zanaria Saupi Udin |
| Date Deposited: | 19 Apr 2011 04:36 |
| Last Modified: | 11 Nov 2019 03:49 |
| URI: | http://eprints.um.edu.my/id/eprint/773 |
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