Seroprevalence survey of chikungunya virus in Bagan Panchor, Malaysia

Ayu, S.M. and Lai, L.R. and Chan, Y.F. and Hatim, A. and Hairi, N.N. and Ayob, A. and Sam, I.C. (2010) Seroprevalence survey of chikungunya virus in Bagan Panchor, Malaysia. American Journal of Tropical Medicine and Hygiene, 83 (6). pp. 1245-1248. ISSN 0002-9637

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Abstract

In 2006, an outbreak of Chikungunya virus (CHIKV) of the Asian genotype affected over 200 people in Bagan Panchor village in Malaysia. One year later, a post-outbreak survey was performed to determine attack rate, asymptomatic rate, and post-infection sequelae. Findings were compared with recent CHIKV outbreaks of the Central/East African genotype. A total of 180 residents were interviewed for acute symptoms and post-infection physical quality of life and depressive symptoms. Sera from 72 residents were tested for CHIKV neutralizing antibodies. The estimated attack rate was 55.6, and 17.5 of infected residents were asymptomatic. Arthralgia was reported up to 3 months after infection, but there were no reports of long-term functional dependence or depression. Symptomatic and seropositive residents were significantly more likely to live in the area with the most dense housing and commercial activities. CHIKV had a high attack rate and considerable clinical impact during the Bagan Panchor outbreak.

Item Type: Article
Additional Information: Times Cited: 4 Ayu, Said Mas Lai, Li Rong Chan, Yoke Fun Hatim, Ahmad Hairi, Noran Naqiah Ayob, Asiah Sam, I-Ching
Subjects: R Medicine
Divisions: Faculty of Medicine
Depositing User: Ms azrahani halim
Date Deposited: 15 Jul 2013 07:12
Last Modified: 06 Jan 2015 05:20
URI: http://eprints.um.edu.my/id/eprint/7336

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