Detection of pbp2b and ermB genes in clinical isolates of Streptococcus pneumoniae.

Kumari, Navindra and Navaratnam, Parasakthi and Sekaran, Shamala Devi (2008) Detection of pbp2b and ermB genes in clinical isolates of Streptococcus pneumoniae. Journal of Infection in Developing Countries, 2 (3). pp. 193-9. ISSN 2036-6590

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Official URL: http://www.ncbi.nlm.nih.gov/pubmed/19738350

Abstract

The characterization of pneumococcal isolates for penicillin and erythromycin resistance genes could be useful to predict the susceptibility of these isolates to other antibiotics, especially beta-lactams drugs. We have developed an assay with a shorter turnaround time to determine the species and resistance profile of Streptococcus pneumoniae with respect to penicillin and macrolides using the Real Time PCR format with fluorescent labeled Taqman probes, hence facilitating earlier and more definitive antimicrobial therapy which may lead to better patient management.

Item Type: Article
Additional Information: Department of Medical Microbiology, Faculty of Medicine, University of Malaya 50603 Kuala Lumpur, Malaysia
Uncontrolled Keywords: Aminoacyltransferases/genetics; Aminoacyltransferases/isolation & purification;
Subjects: R Medicine > R Medicine (General)
Divisions: Faculty of Medicine > School of Biological Sciences
Depositing User: Mr. Faizal Hamzah
Date Deposited: 16 Apr 2011 02:44
Last Modified: 07 Aug 2017 03:40
URI: http://eprints.um.edu.my/id/eprint/725

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