Tan, P.C. and Aziz, A.Z. and Ismail, Ikram Shah and Omar, S.Z. (2012) Gamma-glutamyltransferase, alanine transaminase and aspartate transaminase levels and the diagnosis of gestational diabetes mellitus. Clinical Biochemistry, 45 (15). pp. 1192-1196. ISSN 0009-9120, DOI https://doi.org/10.1016/j.clinbiochem.2012.05.025.
Full text not available from this repository.Abstract
Objectives: To evaluate gamma-glutamyltransferase (GGT), alanine transaminases (ALT) and aspartate transaminases (AST) levels and prevalent gestational diabetes mellitus (GDM). Design and methods: Random plasma glucose, GGT, ALT and AST and the 50-g glucose challenge test were done on antenatal women followed by diagnostic 3-point 75-g oral glucose tolerance test within two weeks. GDM was diagnosed by ADA (2011) criteria. Results: The GDM rate was 12.2 (319/2610). Mean GGT level was higher in GDM women, 18 12 vs. 16 11 IU/L; P=0.03. The risk for GDM was higher for women in the highest GGT quartile band compared to the lowest: RR 1.35 95CI 1.0-1.8; P=0.04. However, after adjustment for confounders, GGT was no longer associated with GDM. There was no correlation between ALT and AST levels and GDM. Conclusions: Liver transaminases do not predict GDM in contrast to type 2 diabetes. (C) 2012 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.
| Item Type: | Article |
|---|---|
| Funders: | UNSPECIFIED |
| Additional Information: | Times Cited: 0 Tan, Peng Chiong Aziz, Ainul Zahaniah Ismail, Ikram Shah Omar, Siti Zawiah |
| Uncontrolled Keywords: | Gamma-glutamyltransferase; Alanine transaminases; Aspartate transaminases; Gestational diabetes; Glucose tolerance test; Glucose challenge test; Pregnancy |
| Subjects: | R Medicine |
| Divisions: | Faculty of Medicine |
| Depositing User: | Ms Haslinda Lahuddin |
| Date Deposited: | 11 Jul 2013 02:39 |
| Last Modified: | 02 Aug 2019 02:07 |
| URI: | http://eprints.um.edu.my/id/eprint/7205 |
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