Chronic neutrophilic leukaemia.

Gan ., GG; Pasagna , JF.; Eow , GI.; Nadarajan , VS. (2007) Chronic neutrophilic leukaemia. Singapore Medical Journal, 48 (3). e74-6. ISSN 0037-5675

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Chronic neutrophilic leukaemia is a rare myeloproliferative disease characterised by splenomegaly, sustained neutrophilia, raised vitamin B12 level and absence of the Philadelphia chromosome. We report a 74-year-old man who presented first with Sweet's syndrome and subsequently leukocytosis. He had splenomegaly, a raised vitamin B12 level, serum uric acid and neutrophil alkaline phosphatase score. Cytogenetic study of the marrow was normal and peripheral blood for BCR-ABL gene transcript was not detectable. He subsequently passed away with bronchopneumonia.

Item Type: Article
  1. Gan ., GG
  2. Pasagna , JF.
  3. Eow , GI.
  4. Nadarajan , VS.
Journal or Publication Title: Singapore Medical Journal
Uncontrolled Keywords: Aged; Angiogenesis Inhibitors/therapeutic use; Fatal Outcome;
Subjects: R Medicine > RC Internal medicine
Divisions: Faculty of Medicine
Depositing User: Mr. Faizal Hamzah
Date Deposited: 24 Mar 2011 13:08
Last Modified: 24 Mar 2011 13:08

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