Antibacterial Evaluation of Some Schiff Bases Derived from 2-Acetylpyridine and Their Metal Complexes

Gwaram, N.S. and Ali, H.M. and Khaledi, H. and Abdulla, M.A. and Hadi, A.H.A. and Thong, Kwai Lin and Ching, C.L. and Ooi, C.L. (2012) Antibacterial Evaluation of Some Schiff Bases Derived from 2-Acetylpyridine and Their Metal Complexes. Molecules, 17 (5). pp. 5952-5971. ISSN 1420-3049

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Abstract

A series of Schiff bases derived from 2-acetylpyridne and their metal complexes were characterized by elemental analysis, NMR, FT-IR and UV-Vis spectral studies. The complexes were screened for anti-bacterial activity against Methicillin-resistant Staphylococcus aureus (MRSA), Acinetobacter baumanni (AC), Klebsiella pneumonie (KB) and Pseudomonas aeruginosa (PA) using the disc diffusion and micro broth dilution assays. Based on the overall results, the complexes showed the highest activities against MRSA while a weak antibacterial activity was observed against A. baumanii and P. aeruginosa.

Item Type: Article
Uncontrolled Keywords: Schiff bases; metal complexes; x-ray crystallography; anti-bacteria
Subjects: Q Science > Q Science (General)
Q Science > QR Microbiology
Divisions: Faculty of Science > Institute of Biological Sciences
Depositing User: miss munirah saadom
Date Deposited: 14 Jan 2013 06:27
Last Modified: 30 Jan 2019 01:27
URI: http://eprints.um.edu.my/id/eprint/5429

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