Saniasiaya, Jeyasakthy and Kulasegarah, Jeyanthi (2023) The link between airway reflux and non-acid reflux in children: a review. Brazilian Journal of Otorhinolaryngology, 89 (2). pp. 329-338. ISSN 1808-8694, DOI https://doi.org/10.1016/j.bjorl.2022.05.002.
Full text not available from this repository.Abstract
Objective:Airway reflux, a member of extra-esophageal reflux, has been linked to countless respiratory pathologies amongst children. The advent of novel instrumentation has enabled the discovery of non-acid reflux which was postulated as the main culprit of airway reflux. The objective of this review is to outline the association between non-acid reflux and airway reflux in children. Methods:A comprehensive review of recent literature on non-acid reflux and airway reflux in children was conducted. Studies ranged from January 2010 till November 2021 were searched over a period of a month: December 2021. Results:A total of eleven studies were identified. All studies included in this review revealed a strong link between non-acid reflux and airway reflux in children. 6 of the included studies are prospective studies, 3 retrospective studies, 1 cross-section study, and type of study was not mentioned in 1 study. The most common reported respiratory manifestation of non-acid reflux in children was chronic cough (7 studies). Predominant non-acid reflux was noted in 4 studies. The total number of children in each study ranges from 21 to 150 patients. MII-pH study was carried out in all studies included as a diagnostic tool for reflux investigation. Conclusion:Non-acid reflux is the culprit behind airway reflux as well as other myriads of extra-esophageal manifestations in children. Multicentre international studies with a standardized protocol could improve scientific knowledge in managing non-acid reflux in airway reflux amongst children. & COPY; 2022 Associacao Brasileira de Otorrinolaringologia e Cirurgia C & PRIME;ervico-Facial. Published by Elsevier Editora Ltda. This is an open access article under the CC BY license (http:// creativecommons.org/licenses/by/4.0/).
| Item Type: | Article |
|---|---|
| Funders: | UNSPECIFIED |
| Uncontrolled Keywords: | Gastroesophageal reflux; Laryngopharyngeal reflux; Airway reflux; Non-acid reflux; Children |
| Subjects: | R Medicine > RF Otorhinolaryngology |
| Divisions: | Faculty of Medicine > Otorhinolaryngology Department |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 21 Jul 2025 08:25 |
| Last Modified: | 21 Jul 2025 08:25 |
| URI: | http://eprints.um.edu.my/id/eprint/50846 |
Actions (login required)
 |
View Item |
